Scholarship of Discovery
We are investigating using the Diels-Alder and retro-Diels-Alder reactions as a potential “catch/release” strategy for isolating Salvinorin A from plant samples (Salvia divinorum), hopefully to improve the current method, which is very long and laborious. Salvinorin A has analgesic activity by activating the kappa opioid receptor, not the mu receptor, and thus it has potential for being developed into a non-addicting analgesic.
Armstrong, Douglas and Smith, Logan, "Progress toward the Development of a "Catch/Release" Strategy for Isolating Salvinorin A, From Plant Materails Including Microwave Promotion" (2017). Faculty Scholarship – Chemistry. 8.
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