Subject-specific, multiscale simulation of electrophysiology: a software pipeline for image-based models and application examples
Document Type
Article
Peer Reviewed
1
Publication Date
6-13-2009
Scholarship Domain(s)
Scholarship of Discovery
Abstract
Many simulation studies in biomedicine are based on a similar sequence of processing steps, starting from images and running through geometric model generation, assignment of tissue properties, numerical simulation and visualization of the results--a process known as image-based geometric modelling and simulation. We present an overview of software systems for implementing such a sequence both within highly integrated problem-solving environments and in the form of loosely integrated pipelines. Loose integration in this case indicates that individual programs function largely independently but communicate through files of a common format and support simple scripting, so as to automate multiple executions wherever possible. We then describe three specific applications of such pipelines to translational biomedical research in electrophysiology.
Recommended Citation
Lew, Seok, "Subject-specific, multiscale simulation of electrophysiology: a software pipeline for image-based models and application examples" (2009). Faculty Scholarship – Engineering. 4.
https://digitalcommons.olivet.edu/engn_facp/4