Scholarship of Discovery
The Drosophila melanogaster meiotic drive system Segregation Distorter (SD) has been a topic of great interest over the past decades due to its implications for fertility issues in fruit flies and other species as well. Several genes have been associated with this system; however, little research has focused on a particular one of these genes—the Modifier of SD. The location of this modifier gene is still unknown, so multiple deleted segments of DNA that compose a suspect area along the 2nd chromosome were tested here to see if some level of distortion is established in the absence of these segments. The DNA region from chromosomal segments 43E9 to 43E18 showed the highest level of distortion (k value = 0.828), so genes within this segment were tested for a possible correlation to Modifier of SD. The three genes torso, saxophone, and CG30497 were examined for this correlation, and torso showed a significant k value (0.689), indicating a possible relation to Modifier of SD.
Craven, Samuel, "Locating the Modifier of Segregation Distorter in Drosophila Melanogaster" (2013). Honors Program Projects. 34.