Document Type
Article
First Advisor
Doug Armstrong
Publication Date
5-25-2017
Scholarship Domain(s)
Scholarship of Discovery
Abstract
We are proposing 1-anilino-8-(mercaptoamino)-1,8-octadione as a compound of potential pharmaceutical value. The addition of carbon disulfide to sodium trimethylsilanolate to yield a xanthate product has been analyzed and refined to a 70% yield. Several methods of aminating the xanthate product to yield a sulfenamide have been attempted and analyzed. Multiple attempts have been made to benzoylate the sulfenamide product with little success, with many concerns stemming from the unsuccessful amination reactions.
Recommended Citation
Sprunger, Macy, "Partial Preparation of 1-Anilino-8-(Mercaptoamino)-1,8-Octadione as a Potential Therapeutic Agent for the Treatment of Huntington’s Disease and Selected Cancers" (2017). Honors Program Projects. 69.
https://digitalcommons.olivet.edu/honr_proj/69
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Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Comments
Honors Cohort 7. Graduation date 2017.