Faculty Mentor(s)
Prof. Schimmel
For Communication to Presenters & Mentors
jddittmer@olivet.edu, cserpe@olivet.edu, sstaranchuk@olivet.edu, kaschimmel@olivet.edu
Project Type
Senior Design Project
Scholarship Domain(s)
Scholarship of Discovery
Presentation Type
Presentation
Abstract
This study presents an investigation of the agitated tank mixing dynamics across various scales, including lab, two pilot, and full scales, focusing on human blood plasma Kistler-Nitschmann-Cohn (KNC) I+II+III suspensions. The methods employed are empirical tank mixing correlations within the KaeMix software package and Computational Fluid Dynamics (CFD) modeling using ANSYS Fluent. Tank and agitator geometries were generated in ANSYS Workbench and meshed in ANSYS Fluent with varied cell sizes to capture detailed dynamics near the agitators and in the bulk fluid. Kaemix analysis provided rapid computation of bulk mixing times at different scales. Beyond simulations, the project aims to establish set points for pilot-scale and small-scale mixing vessels, ensuring conditions closely resemble full-scale manufacturing.
Permission Type
This work is licensed under a Creative Commons Attribution 4.0 License.
Scaling and Optimizing Agitated Tanks for the Homogenization of Complex Biological Suspensions
Reed 330
This study presents an investigation of the agitated tank mixing dynamics across various scales, including lab, two pilot, and full scales, focusing on human blood plasma Kistler-Nitschmann-Cohn (KNC) I+II+III suspensions. The methods employed are empirical tank mixing correlations within the KaeMix software package and Computational Fluid Dynamics (CFD) modeling using ANSYS Fluent. Tank and agitator geometries were generated in ANSYS Workbench and meshed in ANSYS Fluent with varied cell sizes to capture detailed dynamics near the agitators and in the bulk fluid. Kaemix analysis provided rapid computation of bulk mixing times at different scales. Beyond simulations, the project aims to establish set points for pilot-scale and small-scale mixing vessels, ensuring conditions closely resemble full-scale manufacturing.